TyG Index Calculator
The triglyceride-glucose (TyG) index combines two routine fasting labs into a single number that research links to insulin resistance and cardiometabolic risk. It requires no insulin assay — just the triglycerides and glucose from a standard metabolic panel.
From your lipid panel
After at least 8 hours without eating
Enter your values above to see your results.
Want a deeper AI analysis of your symptoms?
Our free 3-minute assessment maps your symptoms to possible root cause patterns and emails you a personalized report.
Take the free health assessment →For practitioners: see the Fatigue Health Assessment →
How it works
The formula
TyG = ln( fasting triglycerides mg/dL × fasting glucose mg/dL ÷ 2 ). The natural log compresses the scale, so small differences at the top end matter more than they look.
Why it works without an insulin assay
Insulin tests are expensive and not standardized across labs. Triglycerides and glucose are on every standard panel. Elevations in both reflect the same underlying energy-handling dysfunction that insulin resistance produces, which is why their combination tracks HOMA-IR surprisingly well.
Limitations
Cut-offs differ across populations and studies — 8.5 is a commonly cited threshold, not a universal one. Recent illness, alcohol intake, and non-fasting samples all distort triglycerides. Use TyG as one signal among several.
Frequently asked questions
What is a normal TyG index?
In research cohorts, values below ~8.0 are typically seen in insulin-sensitive individuals, 8.0–8.5 is intermediate, and above ~8.5 is associated with higher insulin resistance likelihood. Exact cut-offs vary by population and study.
My labs are in mmol/L — how do I convert?
Glucose: multiply mmol/L by 18 to get mg/dL. Triglycerides: multiply mmol/L by 88.57 to get mg/dL. Then use the calculator normally.
How does TyG compare to HOMA-IR?
Both estimate insulin resistance. HOMA-IR needs a fasting insulin assay; TyG uses triglycerides and glucose, which are cheaper and already on most panels. Studies show good correlation between the two, and some find TyG performs as well or better for predicting metabolic syndrome.
Is the TyG index a diagnosis?
No. It is a screening marker derived from routine labs. A high value is a prompt to look deeper — not a diagnosis of any condition. Discuss your full panel with a qualified practitioner.
Sources
- Simental-Mendía LE, et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Metab Syndr Relat Disord, 2008.
- Guerrero-Romero F, et al. The product of triglycerides and glucose compared with fasting plasma insulin as a surrogate of insulin sensitivity. J Clin Endocrinol Metab, 2010.
This calculator is for informational purposes only and is not medical advice, diagnosis, or treatment. Reference ranges are general population guidelines — always discuss your lab results with a qualified healthcare professional.